Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)
NCT03924856
Merck Sharp & Dohme LLC
active not recruiting
Urinary Bladder Neoplasms,Muscle Neoplasms
NCT03924856
A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy
NCT03520491
Memorial Sloan Kettering Cancer Center
recruiting
Urinary Bladder Neoplasms
NCT03520491
Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation
NCT05975307
Sun Yat-sen University
not yet recruiting
Urinary Bladder Neoplasms
NCT05975307
Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)
NCT03924895
Merck Sharp & Dohme LLC
recruiting
Urinary Bladder Neoplasms,Muscle Neoplasms
NCT03924895
A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Patients With High-Risk Muscle-Invasive Bladder Cancer Who Are ctDNA Positive Following Cystectomy
NCT04660344
Hoffmann-La Roche
recruiting
Urinary Bladder Neoplasms
NCT04660344
BLASST-1 (Bladder Cancer Signal Seeking Trial): Nivolumab, Gemcitabine, and Cisplatin in Treatment of Muscle Invasive Bladder Cancer (MIBC) Undergoing Cystectomy
NCT03294304
Masonic Cancer Center, University of Minnesota
completed
Urinary Bladder Neoplasms
NCT03294304
Checkpoint Inhibitor and Radiation Therapy in Bulky, Node-Positive Bladder Cancer
NCT04779489
University of Texas Southwestern Medical Center
recruiting
Urinary Bladder Neoplasms
NCT04779489
a Genome-based Platform to Predict Patients That Can Achieve Bladder Preservation in Muscle Invasive Bladder Cancer Patients
NCT04686149
Yonsei University
not yet recruiting
Urinary Bladder Neoplasms
NCT04686149
Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer
NCT04383743
University of Washington
recruiting
Urinary Bladder Neoplasms
NCT04383743
Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer
NCT05581589
University of Washington
recruiting
Urinary Bladder Neoplasms
NCT05581589